The most popularly known blood grouping is the ABO grouping. It is named ABO and not ABC, because "O"" in…

The most popularly known blood grouping is the ABO grouping. It is named ABO and not ABC, because \"O\"" in it refers to having"
A No antigens A and B on RBCs
B Other antigens besides A and B on RBCs
C Overdominance of this type on the genes for A and B types
D One antibody only – either anti-A or anti-B on the RBCs

Detailed Solution

ABO grouping is based on the presence or absence of two surface antigens, A and B, on the RBCs.
Group A has antigen A, group B has antigen B and group AB has both antigens.
Group O has neither antigen A nor antigen B on its RBCs ('O' stands for nil or zero); its plasma has both anti-A and anti-B antibodies.
Since it lacks both antigens, group O blood can be donated to all groups (universal donor).
Hence 'O' refers to having no antigens A and B on RBCs.

Blood Groups in past papers

5 questions from this chapter have appeared across 5 exam years.

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Practise Blood Groups All 5 questions This chapter in 2009 AIPMT