If you suspect major deficiency of antibodies in a person, to which of the following would you look for confirmatory…

If you suspect major deficiency of antibodies in a person, to which of the following would you look for confirmatory evidence?
A serum globulins
B fibrinogen in the plasma
C haemocytes
D serum albumins

Detailed Solution

The major proteins of blood plasma are fibrinogen, globulins and albumins.
Globulins are primarily involved in the defence mechanisms of the body.
Antibodies are immunoglobulins; they belong to the $\gamma$-globulin (gamma globulin) fraction of the serum globulins, while the $\alpha$ and $\beta$ globulins transport hormones and other substances.
So a major deficiency of antibodies will show up as a low level of serum globulins, which is the confirmatory evidence.
Fibrinogen is needed for the clotting or coagulation of blood.
Albumins help in maintaining the osmotic balance of the blood.
Haemocytes are blood cells, not the proteins that make up antibodies.

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Practise Plasma proteins All 2 questions This chapter in 2007 AIPMT-PRE