Cell Cycle and Cell DivisionMitosis - metaphase 1 2022 Phase 2 Easy With respect to metaphase, which of the following statements is incorrect? A Chromosomes lie at the equator of the cell B Complete disintegration of nuclear envelope takes place C Chromosomes are highly condensed D Metaphase chromosomes are made up of four sister chromatids held together by centromere Check Answer Detailed Solution Each metaphase chromosome is made up of two sister chromatids held together by the centromere, not four.