During mitosis ER and nucleolus begin to disappear at

6 2010 AIPMT-PRE Cell Cycle and Cell DivisionMitosis Medium
During mitosis ER and nucleolus begin to disappear at
A Early prophase
B Late prophase
C Early metaphase
D Late metaphase

Detailed Solution

Prophase is the first stage of mitosis: chromosomal material condenses and the centrioles begin to move towards the opposite poles.
The Golgi complexes, endoplasmic reticulum, nucleolus and nuclear envelope start disappearing as prophase begins.
By the end of prophase (late prophase) they are no longer visible under the microscope, which means their disappearance must have begun earlier.
Hence the ER and nucleolus begin to disappear at early prophase.

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