2004 AIPMT Cell Cycle and Cell DivisionPhases of cell cycle Easy Question 3 of 4 in Phases of cell cycle

In the somatic cell cycle :-

A DNA replication takes place in S-phase
B A short interphase is followed by a long mitotic phase
C $G_2$ phase follows mitotic phase
D In $G_1$ phase DNA content is double the amount of DNA present in the original cell

The answer is A.

Solution

The cell cycle consists of interphase ($G_1$, S and $G_2$ phases) followed by the M phase (mitosis).
DNA replication takes place in the S (synthesis) phase. The DNA content doubles from 2C to 4C, while the chromosome number stays the same; true.
Interphase is long (about 95 percent of the cycle) and the M phase is short (in a 24 hour human cell cycle, mitosis lasts about 1 hour). So the second statement is false.
$G_2$ follows the S phase, not the mitotic phase; $G_1$ follows mitosis. So the third statement is false.
In $G_1$ the DNA content is 2C, the same as in the original cell, not double. So the fourth statement is false.
So in the somatic cell cycle, DNA replication takes place in the S phase.

Concept S phase and DNA replication

Phases of cell cycle in past papers

4 questions from this chapter have appeared across 4 exam years.