The main organelle involved in modification and routing of newly synthesized proteins to their destinations is -

The main organelle involved in modification and routing of newly synthesized proteins to their destinations is -
A Endoplasmic Reticulum
B Lysosome
C Mitochondria
D Chloroplast

Detailed Solution

Proteins destined for secretion, for the plasma membrane or for lysosomes are synthesised on ribosomes attached to the rough endoplasmic reticulum.
As they enter the lumen of the ER they are folded, and their modification begins (for example the addition of oligosaccharides, i.e. glycosylation).
From the ER they are packed into vesicles and sent to the Golgi apparatus for further modification, sorting and dispatch to their destinations.
Among the given choices, the endoplasmic reticulum is the organelle involved in the modification and routing of newly synthesised proteins.
Lysosomes digest materials, and mitochondria and chloroplasts are concerned with energy conversion.
So the answer is the endoplasmic reticulum.

Endomembrane system in past papers

5 questions from this chapter have appeared across 4 exam years.

Keep going

Practise Endomembrane system All 5 questions This chapter in 2005 AIPMT