Chemical Coordination and Integration

The ovaries are the primary female sex organs and also endocrine glands. They secrete estrogen (by the growing follicles) and progesterone (by the corpus luteum).
If both ovaries are removed (ovariectomy), these hormones are no longer produced, so the estrogen level in blood falls sharply.
Oxytocin and prolactin come from the pituitary, and gonadotrophin releasing factor comes from the hypothalamus; GnRH and gonadotrophins actually rise when the ovaries are removed, because there is no negative feedback from estrogen.
So estrogen is decreased in blood.

Adrenaline (epinephrine) is secreted by the adrenal medulla in emergencies (fight or flight).
It acts directly on the SA node (pacemaker) of the heart, increasing the rate and strength of the heartbeat.
It also raises blood glucose, dilates the pupils and bronchi, and increases alertness.
So adrenaline directly affects the S.A. node.

STH (somatotropic hormone, or growth hormone) is secreted by the anterior pituitary.
Excess of growth hormone in childhood, before the growth plates close, causes gigantism (very tall stature).
Excess of growth hormone in adults, after the long bones have stopped growing, causes acromegaly: enlargement of bones of the face, hands and feet, and thickening of soft tissues.
Thyroxine deficiency causes cretinism and myxoedema, and thyroxine excess causes Graves' disease.
So acromegaly is caused by excess of S.T.H.