Duodenum has characteristic Brunner's glands which secrete two hormones called -
A
Secretin, Cholecystokinin
B
Prolactin, parathormone
C
Estradiol, progesterone
D
Kinase, estrogen
The answer is A.
Solution
The duodenum is the first part of the small intestine. Its submucosa contains Brunner's glands, and its mucosa contains endocrine cells. The duodenal mucosa produces two important gastrointestinal hormones: Secretin: stimulates the pancreas to secrete a watery juice rich in bicarbonate, which neutralises the acidic chyme. Cholecystokinin (CCK): stimulates the pancreas to secrete enzymes and the gall bladder to contract and release bile. Prolactin, parathormone, estradiol and progesterone are produced by the pituitary, parathyroid and ovaries, not by the duodenum. So the two duodenal hormones are secretin and cholecystokinin. (Strictly, Brunner's glands secrete an alkaline mucus, while these hormones come from endocrine cells of the duodenal mucosa; the question links them to the duodenum.)
ConceptDuodenal hormones secretin and CCK
Chemical Coordination and Integration in past papers
85 questions from this chapter have appeared across 26 exam years.