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Which of the following hormones can play a significant role in osteoporosis?
Explanation
Low estrogen and excess PTH both cause bone loss.
Detailed Solution
Estrogen promotes the activity of osteoblasts and inhibits osteoclasts. In an ageing female, osteoporosis occurs due to deficiency of estrogen.
Parathormone promotes mobilisation of calcium from bone into blood. Excessive activity of parathormone causes demineralisation, leading to osteoporosis.