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Select incorrect statement, regarding chemical structure of insulin.
A
Mature insulin molecule consists of three polypeptide chains-A, B and C.
B
Insulin is synthesized as prohormone which contains extra stretch of C-peptide.
C
C-peptide is not present in mature insulin molecule.
D
Polypeptide chains A and B are linked by disulphide bridges.
Detailed Solution
Mature insulin consists of only two polypeptide chains, A and B (linked by disulphide bridges), not three chains — so the statement that it consists of three chains (A, B and C) is incorrect. Insulin is synthesised as a prohormone (proinsulin) containing an extra C-peptide segment, which is removed before the mature hormone is formed.
