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The principal nitrogenous excretory compound in humans is synthesised
A
In the liver but eliminated mostly through kidneys
B
In kidneys but eliminated mostly through liver
C
In kidneys as well as eliminated by kidneys
D
In liver and also eliminated by the same through bile
Detailed Solution
Humans are ureotelic; the principal nitrogenous waste is urea.
Ammonia produced by the metabolism of amino acids is converted into urea in the liver through the ornithine (urea) cycle.
Urea is released into the blood, filtered out by the kidneys and excreted in the urine.
Only small amounts leave the body by other routes such as sweat.
Hence it is synthesised in the liver but eliminated mostly through the kidneys.
Ammonia produced by the metabolism of amino acids is converted into urea in the liver through the ornithine (urea) cycle.
Urea is released into the blood, filtered out by the kidneys and excreted in the urine.
Only small amounts leave the body by other routes such as sweat.
Hence it is synthesised in the liver but eliminated mostly through the kidneys.