2022 Phase 2 Human Health and DiseaseCell-mediated immunity - graft rejection Easy Question 27 of 121 in Human Health and Disease

Which of the following reasons is mainly responsible for graft rejection in transplantation of organs?

A Cell-mediated response
B Inability of recipient to differentiate between 'self' and 'non-self' tissues/cells
C Humoral immune response only
D Auto-immune response

The answer is A.

Solution

Tissue and blood group matching are essential before a transplant. Graft rejection is mainly due to the cell-mediated immune response (T lymphocytes).

Concept Cell-mediated immunity - graft rejection

Human Health and Disease in past papers

121 questions from this chapter have appeared across 27 exam years.