To which type of barriers under innate immunity, do the saliva in the mouth and the tears from the eyes,…

To which type of barriers under innate immunity, do the saliva in the mouth and the tears from the eyes, belong?
A Physiological barriers
B Physical barriers
C Cytokine barriers
D Cellular barriers

Detailed Solution

Innate immunity is the non-specific type of defence that is present at the time of birth. It consists of four types of barriers.
Physical barriers: the skin, and the mucus coating of the epithelium lining the respiratory, gastrointestinal and urogenital tracts.
Physiological barriers: acid in the stomach, saliva in the mouth and tears from the eyes; all of these prevent microbial growth. Saliva and tears contain the enzyme lysozyme, which destroys bacterial cell walls.
Cellular barriers: certain leucocytes such as polymorpho-nuclear leucocytes (neutrophils), monocytes and natural killer cells, as well as macrophages in the tissues, which phagocytose and destroy microbes.
Cytokine barriers: virus-infected cells secrete proteins called interferons, which protect non-infected cells from further viral infection.
So saliva in the mouth and tears from the eyes belong to the physiological barriers.

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4 questions from this chapter have appeared across 4 exam years.

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Practise Innate immunity All 4 questions This chapter in 2008 AIPMT