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Which one of the following does not follow the central dogma of molecular biology?
A
HIV
B
Pea
C
$Mucor$
D
$Chlamydomonas$
Detailed Solution
The central dogma states that genetic information flows from DNA to RNA to protein.
HIV is a retrovirus with an RNA genome. After entering the host cell, its RNA is copied into DNA by the enzyme reverse transcriptase.
Here information flows from RNA to DNA, the reverse of the central dogma (this is called reverse transcription or teminism).
Pea, $Mucor$ and $Chlamydomonas$ have DNA as genetic material and follow the normal DNA → RNA → protein flow.
Hence HIV does not follow the central dogma.
HIV is a retrovirus with an RNA genome. After entering the host cell, its RNA is copied into DNA by the enzyme reverse transcriptase.
Here information flows from RNA to DNA, the reverse of the central dogma (this is called reverse transcription or teminism).
Pea, $Mucor$ and $Chlamydomonas$ have DNA as genetic material and follow the normal DNA → RNA → protein flow.
Hence HIV does not follow the central dogma.