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Which of the following are the post-transcriptional events in an eukaryotic cell?
A. Transport of pre-mRNA to cytoplasm prior to splicing.
B. Removal of introns and joining of exons.
C. Addition of methyl group at 5' end of hnRNA.
D. Addition of adenine residues at 3' end of hnRNA.
E. Base pairing of two complementary RNAs.
Choose the correct answer from the options given below:
A. Transport of pre-mRNA to cytoplasm prior to splicing.
B. Removal of introns and joining of exons.
C. Addition of methyl group at 5' end of hnRNA.
D. Addition of adenine residues at 3' end of hnRNA.
E. Base pairing of two complementary RNAs.
Choose the correct answer from the options given below:
Explanation
Post-transcriptional modifications of hnRNA include splicing (B), 5'-capping (C), and 3'-polyadenylation (D).
Detailed Solution
In eukaryotic nucleus, newly synthesized hnRNA undergoes: (B) Splicing (introns removed, exons joined), (C) Capping (7-methylguanosine added to 5' end), and (D) Tailing (200-300 adenylate residues added at 3' end). Pre-mRNA is not transported to cytoplasm before splicing, so only B, C, and D are correct.