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Four healthy people in their twenties got involved in injuries resulting in damage and death of a few cells of the following. Which of the cells are least likely to be replaced by new cells -
A
Osteocytes
B
Liver cells
C
Neurons
D
Malpighian layer of the skin
Detailed Solution
Mature neurons are highly specialised cells that have lost the ability to divide (they remain in the $G_0$ phase and lack centrioles for division).
So when neurons are damaged or die, they are generally not replaced by new cells.
Liver cells can divide and regenerate the liver after injury.
The Malpighian (germinative) layer of the skin divides continuously and replaces the cells of the epidermis.
Bone has osteoblasts that can form new bone cells (osteocytes) during repair.
So the cells least likely to be replaced are the neurons.
So when neurons are damaged or die, they are generally not replaced by new cells.
Liver cells can divide and regenerate the liver after injury.
The Malpighian (germinative) layer of the skin divides continuously and replaces the cells of the epidermis.
Bone has osteoblasts that can form new bone cells (osteocytes) during repair.
So the cells least likely to be replaced are the neurons.