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Biology
Biotechnology and its Applications
86 questions, each with its answer.
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What is true for monoclonal antibodies : -Monoclonal antibodies are identical antibodies produced by a single clone of cells, and they are specific for one antigen (one epitope).
They are made by hybridoma technology (Kohler and Milstein, 1975): an antibody-producing B-lymphocyte (from a mouse immunised with the antigen) is fused with a myeloma (cancer) cell.
So the hybridoma cell is derived from two different parent cells: the B-cell provides the ability to make the specific antibody and the myeloma cell provides the ability to divide indefinitely.
So, as per the answer key, monoclonal antibodies are obtained from different parents (two fused parent cells) and are for one antigen.
That is every 2001 AIPMT question in Biotechnology and its Applications.
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