Which one of the following pairs of hormones are the examples of those that can easily pass through the cell…

Which one of the following pairs of hormones are the examples of those that can easily pass through the cell membrane of the target cell and bind to a receptor inside it (mostly in the nucleus)?
A Cortisol, testosterone
B Insulin, glucagon
C Thyroxin, Insulin
D Somatostatin, oxytocin

Detailed Solution

Steroid hormones such as cortisol and testosterone are lipid soluble. They pass through the cell membrane and bind to intracellular receptors, mostly in the nucleus, and regulate gene expression.
Insulin, glucagon, somatostatin and oxytocin are peptide or protein hormones; they bind to membrane-bound receptors and act through second messengers.

Mechanism of Hormone Action in past papers

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Practise Mechanism of Hormone Action All 5 questions This chapter in 2012 AIPMT-PRE