2022 Phase 2 Chemical Coordination and IntegrationMechanism of Hormone Action Medium Question 1 of 7 in Mechanism of Hormone Action

FSH which interacts with membrane bound receptors does not enter the target cell.

Reason: Binding of FSH to its receptors generates second messenger (cyclic AMP) for its biochemical and physiological responses.
A Both A and R are true and R is the correct explanation of A
B Both A and R are true but R is NOT the correct explanation of A
C A is true but R is false
D A is false but R is true

The answer is B.

Solution

FSH is a peptide (lipid-insoluble) hormone, so it cannot pass through the membrane and acts through membrane-bound receptors - the assertion is correct. Binding of such hormones to membrane receptors generates second messengers (cAMP) - the reason is also correct, but it does not explain why FSH does not enter the cell (that is due to its lipid insolubility).

Concept Mechanism of hormone action

Mechanism of Hormone Action in past papers

7 questions from this chapter have appeared across 5 exam years.