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Consider the following four statements (a–d) regarding kidney transplant and select the two correct ones out of these.
a. Even if a kidney transplant is proper the recipient may need to take immunosuppressants for a long time
b. The cell-mediated immune response is responsible for the graft rejection
c. The B-lymphocytes are responsible for rejection of the graft
d. The acceptance or rejection of a kidney transplant depends on specific interferons
The two correct statements are
a. Even if a kidney transplant is proper the recipient may need to take immunosuppressants for a long time
b. The cell-mediated immune response is responsible for the graft rejection
c. The B-lymphocytes are responsible for rejection of the graft
d. The acceptance or rejection of a kidney transplant depends on specific interferons
The two correct statements are
A
a & b
B
b & c
C
c & d
D
a & c
Detailed Solution
The body is able to differentiate 'self' from 'non-self', so a grafted organ from another person is recognised as foreign.
Tissue matching and blood group matching are essential before any transplant, and even after this the patient has to take immunosuppressants all his or her life. So (a) is correct.
Graft rejection is brought about by the cell-mediated immune response, i.e., by T-lymphocytes. So (b) is correct and (c), which names B-lymphocytes, is wrong.
Interferons are proteins secreted by virus-infected cells to protect non-infected cells from viral infection; they do not decide the acceptance of a graft. So (d) is wrong.
Hence the two correct statements are a and b.
Tissue matching and blood group matching are essential before any transplant, and even after this the patient has to take immunosuppressants all his or her life. So (a) is correct.
Graft rejection is brought about by the cell-mediated immune response, i.e., by T-lymphocytes. So (b) is correct and (c), which names B-lymphocytes, is wrong.
Interferons are proteins secreted by virus-infected cells to protect non-infected cells from viral infection; they do not decide the acceptance of a graft. So (d) is wrong.
Hence the two correct statements are a and b.