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Immunity
Appears in
Concepts tested here
- Graft rejection 2
- Cell-mediated immunity
- Colostrum antibodies
- Passive immunity
All Questions
2015 AIPMT-II 2 questions
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Grafted kidney may be rejected in a patient due to
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Which of the following immunoglobulins does constitute the largest percentage in human milk?
2013 NEET 1 question
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The cell-mediated immunity inside the human body is carried out by:T-lymphocytes mediate cell-mediated immunity (CMI). B-lymphocytes produce antibodies for the humoral response.
2012 AIPMT-MAINS 1 question
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Which one of the following statements is correct with respect to immunity?In a snake bite, a quick immune response is needed, so preformed antibodies against the venom (antivenom) are injected. This is passive immunisation and the statement is correct.
Graft rejection is brought about by cell-mediated immunity, i.e., by T-lymphocytes, not by B-lymphocytes.
Antibodies are produced by B-lymphocytes (plasma cells); T-lymphocytes do not secrete antibodies but help B-cells.
Each antibody molecule has four peptide chains: two light chains and two heavy chains ($H_2L_2$), not four light chains.
Hence the correct statement is that preformed antibodies need to be injected to treat the bite of a viper.
2010 AIPMT-PRE 1 question
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Consider the following four statements (a–d) regarding kidney transplant and select the two correct ones out of these.
a. Even if a kidney transplant is proper the recipient may need to take immunosuppressants for a long time
b. The cell-mediated immune response is responsible for the graft rejection
c. The B-lymphocytes are responsible for rejection of the graft
d. The acceptance or rejection of a kidney transplant depends on specific interferons
The two correct statements areThe body is able to differentiate 'self' from 'non-self', so a grafted organ from another person is recognised as foreign.
Tissue matching and blood group matching are essential before any transplant, and even after this the patient has to take immunosuppressants all his or her life. So (a) is correct.
Graft rejection is brought about by the cell-mediated immune response, i.e., by T-lymphocytes. So (b) is correct and (c), which names B-lymphocytes, is wrong.
Interferons are proteins secreted by virus-infected cells to protect non-infected cells from viral infection; they do not decide the acceptance of a graft. So (d) is wrong.
Hence the two correct statements are a and b.