In E. coli, during lactose metabolism repressor binds to : -
A
Regulator gene
B
Operator gene
C
Structural gene
D
Promoter gene
The answer is B.
Solution
In the lac operon, the regulator (i) gene produces a repressor protein. In the absence of lactose, the repressor binds to the operator gene, which lies between the promoter and the structural genes. This blocks RNA polymerase and switches off transcription of the structural genes (z, y, a). When lactose (allolactose, the inducer) is present, it binds to the repressor and makes it inactive, so it can no longer bind the operator, and the genes are transcribed. So the repressor binds to the operator gene.
ConceptRepressor binds operator
Regulation of Gene Expression – Lac Operon in past papers
6 questions from this chapter have appeared across 6 exam years.