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Biology
Principles of Inheritance and Variation
198 questions from 38 papers, each with its answer.
- 198 questions
- 38 papers
- 5.62% of Biology
Gamete Formation and Independent Assortment
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A male human is heterozygous for autosomal genes A and B and is also hemizygous for hemophilic gene h. What proportion of his sperms will be abh :-Genotype of the man: Aa Bb $X^hY$ (heterozygous for A and B, and hemizygous for h, i.e. one $X^h$ and a Y).
Assuming independent assortment, each gene pair separates independently into the sperms.
Probability of a sperm getting a $= \dfrac{1}{2}$ (A or a)
Probability of getting b $= \dfrac{1}{2}$ (B or b)
Probability of getting the X with h $= \dfrac{1}{2}$ (the other half of the sperms carry Y)
Probability of an abh sperm $= \dfrac{1}{2} \times \dfrac{1}{2} \times \dfrac{1}{2} = \dfrac{1}{8}$
The man forms $2^3 = 8$ types of sperms in equal proportions (ABh, ABY, Abh, AbY, aBh, aBY, abh and abY), and abh is one of them.
So $\dfrac{1}{8}$ of his sperms will be abh.
Inheritance of Three Genes
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A self-fertilizing trihybrid plant forms :-A trihybrid plant is heterozygous for three genes, e.g. AaBbCc.
Number of types of gametes $= 2^n$, where n is the number of heterozygous gene pairs: $2^3 = 8$ (ABC, ABc, AbC, Abc, aBC, aBc, abC, abc).
On self-fertilisation, each of the 8 types of male gametes can fuse with each of the 8 types of female gametes.
Number of zygote combinations $= 8 \times 8 = 64$ (the squares of the Punnett square).
(These give 27 different genotypes and 8 phenotypes in the ratio 27 : 9 : 9 : 9 : 3 : 3 : 3 : 1.)
So the plant forms 8 different gametes and 64 different zygotes.
Dihybrid Cross and Test Cross
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In a plant red fruit (R) is dominant over yellow fruit (r) and tallness (T) is dominant over shortness (t). If a plant with RRTt genotype is crossed with a plant that is rrttGametes of RRTt: RT and Rt (in equal proportion, 1/2 each).
Gametes of rrtt: rt only.
Offspring: RT $\times$ rt = RrTt (red, tall); Rt $\times$ rt = Rrtt (red, short).
So all offspring have red fruit (Rr), because the RRTt parent is homozygous for red.
For height, Tt $\times$ tt gives 1/2 Tt (tall) and 1/2 tt (short).
Ratio: 1 red tall : 1 red short.
So 50% of the offspring will be tall with red fruit.
Cytoplasmic (Maternal) Inheritance
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One of the parents of a cross has a mutation in its mitochondria. In that cross, that parent is taken as a male. During segregation of $F_2$ progenies that mutation is found in -Mitochondrial DNA is inherited through the cytoplasm.
During fertilisation, the egg contributes almost all of the cytoplasm (and mitochondria) to the zygote. The sperm contributes mainly its nucleus; its few mitochondria are lost or destroyed.
So mitochondrial traits show maternal (uniparental) inheritance: they are passed only through the female parent.
Here the parent with the mitochondrial mutation is the male, so its mitochondria are not transmitted to the $F_1$, and therefore not to the $F_2$ either.
So the mutation is found in none of the progenies.
That is every question in Principles of Inheritance and Variation for this filter.
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