2020 Principles of Inheritance and VariationMendelian Disorders Medium Question 3 of 6 in Mendelian Disorders

Select the correct match.

A Phenylketonuria - Autosomal dominant trait
B Sickle cell anaemia - Autosomal recessive trait, chromosome-11
C Thalassemia - X linked
D Haemophilia - Y linked

The answer is B.

Solution

Phenylketonuria – autosomal recessive disorder Sickle cell anaemia – autosomal recessive trait, due to mutation in the gene on chromosome 11 Thalassemia – autosomal recessive disorder Haemophilia – X-linked recessive disorder So the correct match is sickle cell anaemia – autosomal recessive trait, chromosome 11.

Concept mode of inheritance of genetic disorders

Mendelian Disorders in past papers

6 questions from this chapter have appeared across 4 exam years.