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Represented below is the inheritance pattern of a certain type of traits in humans. Which one of the following conditions could be an example of this pattern?
A
Thalassemia
B
Phenylketonuria
C
Sickle cell anaemia
D
Haemophilia
Detailed Solution
The diagram shows the trait passing from the mother to the son and from the father to the daughter, i.e., a criss-cross pattern of inheritance.
Such a pattern is characteristic of genes located on the X chromosome: a son receives his only X chromosome from his mother, while a father passes his X chromosome only to his daughters.
Haemophilia is a sex-linked (X-linked) recessive disorder and follows this pattern.
Thalassemia, phenylketonuria and sickle cell anaemia are autosomal recessive disorders; they are inherited equally by sons and daughters from both parents and do not show criss-cross inheritance.
Hence the condition that could be an example of this pattern is haemophilia.
Such a pattern is characteristic of genes located on the X chromosome: a son receives his only X chromosome from his mother, while a father passes his X chromosome only to his daughters.
Haemophilia is a sex-linked (X-linked) recessive disorder and follows this pattern.
Thalassemia, phenylketonuria and sickle cell anaemia are autosomal recessive disorders; they are inherited equally by sons and daughters from both parents and do not show criss-cross inheritance.
Hence the condition that could be an example of this pattern is haemophilia.