The recessive genes located on X-chromosomes in humans are always-
A
Sub-lethal
B
Expressed in males
C
Expressed in females
D
Lethal
The answer is B.
Solution
Human males have one X and one Y chromosome (XY). Most genes on the X chromosome have no corresponding allele on the Y chromosome. So a male has only one copy of each X-linked gene; he is hemizygous. A recessive allele on his X chromosome has no dominant allele to mask it, and it is always expressed. Females (XX) express an X-linked recessive trait only if they are homozygous recessive; heterozygous females are carriers. Examples: colour blindness and haemophilia are much more common in males. Such genes are not necessarily lethal or sub-lethal. So recessive genes on the X chromosome are always expressed in males.
ConceptHemizygous condition in males
Sex-linked inheritance in past papers
10 questions from this chapter have appeared across 8 exam years.