Which one of the following is a fat-soluble vitamin and its related deficiency disease?

Which one of the following is a fat-soluble vitamin and its related deficiency disease?
A Retinol - Xerophthalmia
B Cobalamine - Beri-beri
C Calciferol - Pellagra
D Ascorbic acid - Scurvy

Detailed Solution

The fat-soluble vitamins are A, D, E and K.
Retinol is vitamin A, a fat-soluble vitamin. Its deficiency causes night blindness and xerophthalmia (dryness of the conjunctiva and cornea). So this pair is correct on both counts.
Cobalamine is vitamin $B_{12}$, which is water soluble; its deficiency causes pernicious anaemia. Beri-beri is caused by the deficiency of thiamine (vitamin $B_1$).
Calciferol is vitamin D, which is fat soluble, but its deficiency causes rickets in children and osteomalacia in adults. Pellagra is caused by the deficiency of niacin (vitamin $B_3$).
Ascorbic acid is vitamin C; it is correctly matched with scurvy, but it is a water-soluble vitamin.
So the fat-soluble vitamin correctly matched with its deficiency disease is Retinol - Xerophthalmia.

Vitamins and Deficiency Diseases in past papers

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Practise Vitamins and Deficiency Diseases All 2 questions This chapter in 2007 AIPMT-PRE