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Vitamins and Deficiency Diseases
Appears in
Concepts tested here
- Beri-beri
- Fat soluble vitamins
All Questions
2007 AIPMT-PRE 1 question
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Which one of the following is a fat-soluble vitamin and its related deficiency disease?The fat-soluble vitamins are A, D, E and K.
Retinol is vitamin A, a fat-soluble vitamin. Its deficiency causes night blindness and xerophthalmia (dryness of the conjunctiva and cornea). So this pair is correct on both counts.
Cobalamine is vitamin $B_{12}$, which is water soluble; its deficiency causes pernicious anaemia. Beri-beri is caused by the deficiency of thiamine (vitamin $B_1$).
Calciferol is vitamin D, which is fat soluble, but its deficiency causes rickets in children and osteomalacia in adults. Pellagra is caused by the deficiency of niacin (vitamin $B_3$).
Ascorbic acid is vitamin C; it is correctly matched with scurvy, but it is a water-soluble vitamin.
So the fat-soluble vitamin correctly matched with its deficiency disease is Retinol - Xerophthalmia.
2005 AIPMT 1 question
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Which group of three of the following five statements (a-e) contains all the three correct statements regarding beri-beri -
(a) A crippling disease prevalent among the native population of sub-Saharan Africa
(b) A deficiency disease caused by lack of thiamine (vitamin $B_1$)
(c) A nutritional disorder in infants and young children when the diet is persistently deficient in essential protein
(d) Occurs in those countries where the staple diet is polished rice
(e) The symptoms are pain from neuritis, paralysis, muscle wasting, progressive oedema, mental deterioration and finally heart failure(b) is correct: beri-beri is a deficiency disease caused by the lack of thiamine (vitamin $B_1$), which is needed as a coenzyme in carbohydrate metabolism.
(d) is correct: it occurs mainly where the staple diet is polished rice, because thiamine is present in the husk and outer layers of the grain, which are removed in polishing.
(e) is correct: the symptoms include pain due to neuritis, paralysis, muscle wasting, progressive oedema, mental deterioration and finally heart failure.
(a) is not correct: beri-beri is not a disease specific to sub-Saharan Africa.
(c) is not correct: a disorder in infants and children due to protein deficiency describes kwashiorkor, not beri-beri.
So the group containing all three correct statements is b, d and e.
