Which group of three of the following five statements (a-e) contains all the three correct statements regarding beri-beri -(a) A…

Which group of three of the following five statements (a-e) contains all the three correct statements regarding beri-beri -
(a) A crippling disease prevalent among the native population of sub-Saharan Africa
(b) A deficiency disease caused by lack of thiamine (vitamin $B_1$)
(c) A nutritional disorder in infants and young children when the diet is persistently deficient in essential protein
(d) Occurs in those countries where the staple diet is polished rice
(e) The symptoms are pain from neuritis, paralysis, muscle wasting, progressive oedema, mental deterioration and finally heart failure
A b, c and e
B a, b and d
C b, d and e
D a, c and e

Detailed Solution

(b) is correct: beri-beri is a deficiency disease caused by the lack of thiamine (vitamin $B_1$), which is needed as a coenzyme in carbohydrate metabolism.
(d) is correct: it occurs mainly where the staple diet is polished rice, because thiamine is present in the husk and outer layers of the grain, which are removed in polishing.
(e) is correct: the symptoms include pain due to neuritis, paralysis, muscle wasting, progressive oedema, mental deterioration and finally heart failure.
(a) is not correct: beri-beri is not a disease specific to sub-Saharan Africa.
(c) is not correct: a disorder in infants and children due to protein deficiency describes kwashiorkor, not beri-beri.
So the group containing all three correct statements is b, d and e.

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Practise Vitamins and Deficiency Diseases All 2 questions This chapter in 2005 AIPMT