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Biomolecules
Enzymes – Competitive Inhibition
1 question from 1 paper, each with its answer.
- question
- 1
- paper
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- years asked, 2017–2026
- 1 of 10
- of Biomolecules
- 0.93%
Concepts tested
- malonate inhibits succinic dehydrogenase
All Questions
2023 1 question
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Malonate inhibits the growth of pathogenic bacteria by inhibiting the activity of
Malonate resembles succinate and competitively inhibits succinic dehydrogenase.
The competitive inhibitor competes with the substrate for the substrate binding site of the enzyme. Consequently, the substrate cannot bind and as a result, the enzyme action declines, e.g., inhibition of succinic dehydrogenase by malonate which closely resembles the substrate succinate in structure. Such competitive inhibitors are often used in the control of bacterial pathogens.