2020 Biotechnology and its ApplicationsGenetically Engineered Insulin Medium Question 4 of 7 in Genetically Engineered Insulin

Which of the following statements is not correct?

A The proinsulin has an extra peptide called C-peptide.
B The functional insulin has A and B chains linked together by hydrogen bonds.
C Genetically engineered insulin is produced in E-Coli.
D In man insulin is synthesised as a proinsulin.

The answer is B.

Solution

In man, insulin is synthesised as a pro-hormone (proinsulin) containing an extra stretch called the C-peptide. Functional insulin has A and B chains linked together by disulphide bridges, not hydrogen bonds – so this statement is not correct. Genetically engineered insulin is produced in $E.\ coli$.

Concept structure of insulin

Genetically Engineered Insulin in past papers

7 questions from this chapter have appeared across 7 exam years.