Looking for classes? Ksquare Career Institute, Bengaluru →
Biotechnology and its Applications
Genetically Engineered Insulin
7 questions from 7 papers, each with its answer.
- questions
- 7
- papers
- 7
- years asked, 2017–2026
- 4 of 10
- of Biotechnology and its Applications
- 8.14%
Appears in
Concepts tested
- Recombinant Human Insulin 2
- Humulin
- insulin-disulphide
- Recombinant insulin
- structure of insulin
- structure of insulin and C-peptide
All Questions
2025 1 question
-
Which of the following genetically engineered organisms was used by Eli Lilly to prepare human insulin?
Eli Lilly used Escherichia coli (a bacterium) to produce chains A and B of human insulin.
In 1983, Eli Lilly synthesized DNA sequences corresponding to chains A and B of human insulin and introduced them into plasmids of the bacterium Escherichia coli to produce Humulin.
2022 1 question
-
Statements related to human Insulin are given below. Which statement(s) is/are correct about genetically engineered Insulin? A. Pro-hormone insulin contain extra stretch of C-peptide B. A-peptide and B-peptide chains of insulin were produced separately in E.coli, extracted and combined by creating disulphide bond between them. C. Insulin used for treating Diabetes was extracted from Cattles and Pigs. D. Pro-hormone Insulin needs to be processed for converting into a mature and functional hormone. E. Some patients develop allergic reactions to the foreign insulin. Choose the most appropriate answer from the options given below.
2021 1 question
-
With regard to insulin choose correct options. A. C-peptide is not present in mature insulin. B. The insulin produced by rDNA technology has C-peptide. C. The pro-insulin has C-peptide. D. A-peptide and B-peptide of insulin are interconnected by disulphide bridges. Choose the correct answer from the options given below.
2020 1 question
-
Which of the following statements is not correct?In man, insulin is synthesised as a pro-hormone (proinsulin) containing an extra stretch called the C-peptide. Functional insulin has A and B chains linked together by disulphide bridges, not hydrogen bonds – so this statement is not correct. Genetically engineered insulin is produced in $E.\ coli$.
2016 1 question
-
The two polypeptides of human insulin are linked together by
Chains A and B of insulin are joined by disulphide bonds.
Insulin is produced by β-cells of the islets of Langerhans as pro-insulin, made of polypeptide chains A and B with a C-peptide. The C-peptide is removed and the A and B chains remain linked by disulphide bridges.
2010 AIPMT-MAINS 1 question
-
Which one of the following is now being commercially produced by biotechnological procedures?Human insulin is produced commercially by recombinant DNA technology.
In 1983 Eli Lilly, an American company, prepared two DNA sequences corresponding to the A and B chains of human insulin and introduced them into plasmids of $E.\ coli$ to produce the insulin chains.
Chains A and B were produced separately, extracted and combined by creating disulphide bonds to form human insulin (humulin).
Nicotine, morphine and quinine are plant alkaloids obtained from tobacco, the opium poppy and $Cinchona$ bark respectively.
Hence insulin is the one produced by biotechnological procedures.
2008 AIPMT 1 question
-
Human insulin is being commercially produced from a transgenic species of:Insulin consists of two short polypeptide chains, chain A and chain B, linked together by disulphide bridges.
In 1983, the American company Eli Lilly prepared two DNA sequences corresponding to the A and B chains of human insulin.
These sequences were introduced into the plasmids of Escherichia coli to produce the insulin chains.
Chains A and B were produced separately, extracted and combined by creating disulphide bonds to form human insulin (humulin).
Rhizobium is a nitrogen-fixing bacterium, Saccharomyces is yeast and Mycobacterium includes disease-causing bacteria; the classical commercial source described in NCERT is the transgenic bacterium Escherichia coli.
So human insulin is commercially produced from a transgenic species of Escherichia.