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Which one of the following is now being commercially produced by biotechnological procedures?
A
Nicotine
B
Morphine
C
Quinine
D
Insulin
Detailed Solution
Human insulin is produced commercially by recombinant DNA technology.
In 1983 Eli Lilly, an American company, prepared two DNA sequences corresponding to the A and B chains of human insulin and introduced them into plasmids of $E.\ coli$ to produce the insulin chains.
Chains A and B were produced separately, extracted and combined by creating disulphide bonds to form human insulin (humulin).
Nicotine, morphine and quinine are plant alkaloids obtained from tobacco, the opium poppy and $Cinchona$ bark respectively.
Hence insulin is the one produced by biotechnological procedures.
In 1983 Eli Lilly, an American company, prepared two DNA sequences corresponding to the A and B chains of human insulin and introduced them into plasmids of $E.\ coli$ to produce the insulin chains.
Chains A and B were produced separately, extracted and combined by creating disulphide bonds to form human insulin (humulin).
Nicotine, morphine and quinine are plant alkaloids obtained from tobacco, the opium poppy and $Cinchona$ bark respectively.
Hence insulin is the one produced by biotechnological procedures.