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Biology
Molecular Basis of Inheritance
200 questions from 38 papers, each with its answer.
- 200 questions
- 38 papers
- 5.67% of Biology
Search for genetic material – Hershey–Chase experiment
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The final proof for DNA as the genetic material came from the experiments of
Hershey–Chase blender experiment proved DNA is the genetic material.
Hershey and Chase gave unequivocal proof, which ended the debate between protein and DNA as the genetic material.
DNA replication – Okazaki fragments
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During DNA replication, Okazaki fragments are used to elongate
Lagging strand is built discontinuously away from the fork.
Two DNA polymerase molecules work simultaneously at the DNA fork, one on the leading strand and the other on the lagging strand. Each Okazaki fragment is synthesised by DNA polymerase on the lagging strand in the $5'\rightarrow3'$ direction. New Okazaki fragments appear as the replication fork opens further. As the first Okazaki fragment appears away from the replication fork, the direction of elongation is away from the replication fork.
Transcription – splicing in eukaryotes
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Spliceosomes are not found in cells of
Bacteria lack introns, so no spliceosomes.
Spliceosomes are used in the removal of introns during post-transcriptional processing of hnRNA in eukaryotes only, as split genes are absent in prokaryotes.
Packaging of DNA – nucleosome
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The association of histone H1 with a nucleosome indicates:
H1 linker histone promotes chromatin condensation.
The association of H1 protein indicates complete formation of the nucleosome. Therefore the DNA is in condensed form (chromatin fibre).
Genetic code – frameshift mutation
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If there are 999 bases in an RNA that codes for a protein with 333 amino acids, and the base at position 901 is deleted such that the length of the RNA becomes 998 bases, how many codons will be altered?
Deletion at base 901 shifts the frame of codons 301–333.
If deletion occurs at the 901st position, the remaining 98 bases, specifying 33 codons, will be altered (frameshift from codon 301 to 333). Note: the opening words of this question ('If there are 999 bases in an RNA that codes for a') are cut off in the source PDF and have been restored from the official NEET 2017 paper.
Types of RNA
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Which of the following RNAs should be most abundant in animal cell?
rRNA makes up ~80% of cellular RNA.
rRNA is the most abundant RNA in an animal cell. It constitutes about 80% of the total RNA of the cell.
That is every question in Molecular Basis of Inheritance for this filter.
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