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Hydrolysis of esters
Concepts tested here
- Electron-withdrawing groups and ester hydrolysis
All Questions
2015 AIPMT-II 1 question
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Which one of the following esters gets hydrolysed most easily under alkaline conditions?Electron-withdrawing groups increase reactivity towards nucleophilic attack by $OH^-$ (and stabilise the leaving phenoxide).
$-NO_2$ is a strong electron-withdrawing group, so p-nitrophenyl acetate is hydrolysed most easily.