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Molecular Basis of Inheritance
Mutations: Point Mutations
1 question from 1 paper, each with its answer.
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Concepts tested
- Transition versus transversion
All Questions
2004 AIPMT 1 question
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In a mutational event, when adenine is replaced by guanine, it is a case of -Point mutations in which one base is substituted for another are of two types.
Transition: a purine is replaced by another purine (A to G or G to A), or a pyrimidine by another pyrimidine (C to T or T to C).
Transversion: a purine is replaced by a pyrimidine or vice versa (e.g. A to T, G to C).
Adenine and guanine are both purines, so replacing adenine by guanine is a transition.
A frameshift mutation is the insertion or deletion of bases, and transcription is not a mutation at all.
So it is a case of transition.