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Principles of Inheritance and Variation
Mutation: Induced Mutations
1 question from 1 paper, each with its answer.
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Concepts tested
- Muller's discovery of X-ray mutagenesis
All Questions
2003 AIPMT 1 question
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Which of the following discoveries resulted in a Nobel Prize : -H. J. Muller showed in 1927, working with Drosophila, that X-rays induce mutations, including sex-linked recessive lethal mutations, which he detected with his ClB method.
For this discovery of the production of mutations by X-ray irradiation, Muller received the Nobel Prize in Physiology or Medicine in 1946.
Cytoplasmic inheritance (Correns) and recombination of linked genes as such were not awarded Nobel Prizes; genetic engineering is a technology rather than a single discovery.
So the discovery that X-rays induce sex-linked recessive lethal mutations resulted in a Nobel Prize.