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Selectable markers
Concepts tested here
- Insertional inactivation
All Questions
2013 NEET 1 question
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The colonies of recombinant bacteria appear white in contrast to blue colonies of non-recombinant bacteria because of:Non-recombinant bacteria have an intact beta-galactosidase gene, so they act on the chromogenic substrate and give blue colonies.
In recombinants the insert inactivates this gene (insertional inactivation), so their colonies stay white.